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Methods: In an ongoing multinational, placebo-controlled, observer-blinded, pivotal efficacy trial, we randomly assigned persons 16 years of age or older in a 1:1 ratio to receive two doses, 21 days apart, of either placebo or the BNT162b2 vaccine candidate (30 μg per dose). BNT162b2 is a lipid nanoparticle-formulated, nucleoside-modified RNA vaccine that encodes a prefusion stabilized, membrane-anchored SARS-CoV-2 full-length spike protein. The primary end points were efficacy of the vaccine against laboratory-confirmed Covid-19 and safety.
It successfully completed 175 days in many centers of Karnataka and became a career highlight for actor Shivarajkumar. This movie's credit goes to Shivarajkumar, Ramu, Om Prakash Rao, Hamsalekha and writers duo M. S. Ramesh and R. Rajshekhar. Half of the film has Hindi dialogue. Om Puri's Hindi punch dialogues got good appreciation. Ex: "Mera joote ka naam bhi Dawood hai" (transl. Even my shoe's name is Dawood), "Maarne ke liye naa tu Godse, marne ke liye naa main Gandhi" (transl. You are neither a Godse to kill, I am neither a Gandhi to be dead) impressed non-Kannada audience also. It's considered one of the best action films in Kannada cinema of all time.
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